Spironolactone + men + breast

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A year-old man with known coronary artery disease and ischemic left ventricular dysfunction presented with chest discomfort. Physical examination revealed severe gynecomastia. The patient had been taking spironolactone 25 mg daily for 8 years as part of his medication regimen for congestive heart failure.

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With gynecomastia, tissue inside the breast glands grows. This can cause female-appearing breasts. Gynecomastia guy-nuh-koh-MAS-tee-uh is swelling of the breast tissue in boys or men, caused by an imbalance of the hormones estrogen and testosterone.

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Articles in the December issue discuss various health issues affecting school-aged children, including acne, eczema and growth disorders. Volume 45, No. Case A man, aged 32 years, presented to his general practitioner GP with a one-month history of increasing bilateral breast swelling Figure 1.

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Spironolactone oral tablet is available as the brand-name drug Aldactone and as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug.

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All medicines have risks and benefits. If you have any concerns about taking this medicine, ask your doctor or pharmacist. Too much aldosterone causes increased amounts of sodium a mineral and water to be retained by the kidneys, while too much potassium is removed from the body.

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What regulates breast tissue proliferation in males that normally prevents the formation of gynecomastia? If both eplerenone and spironolactone are aldosterone antagonists, how then does eplerenone cause less gynecomastia than spironolactone? About Us Disclaimer Contact Us.

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Harper, MD. Harper, a dermatologist in private practice in Birmingham, Ala. Subsequently, the treatment was stopped in all male patients Aesthetic Plast Surg.

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Medically reviewed by Drugs. Last updated on Nov 2, Spironolactone is used in combination with other medicines to treat high blood pressure hypertension and heart failure. Lowering blood pressure can reduce the risk of strokes and heart attacks.

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In mammary tissue, physiological uptake, uptake in benign tumors, and mastopathy have been also reported. Gynecomastia is a common clinical condition consisting of a benign proliferation of male breast glandular tissue; 2 its representative symptom is pain and swelling of the breast. Gynecomastia itself is not a disease but, rather, a symptom of an underlying imbalance in hormonal physiology—specifically, an increase in estrogen action relative to androgen action at the breast tissue level.

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The male breast is much smaller than its female counterpart, and it cannot produce milk. Because of this smaller size and simpler structure, breast disease is much less common in men than women. Still, men can develop important breast problems, both benign and malignant. Early detection is the key to a successful outcome, so every man should understand the basic elements of male breast disease.

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