Dotarem breast

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Guerbet provides radiologists and cardiologists with a complete range of innovative and effective contrast agents that will help them fulfil their mission in the best possible conditions for their patients. Dotarem is indicated for magnetic resonance imaging MRI for cerebral and spinal disease, diseases of the vertebral column and other whole body pathologies, including angiography. Dotarem Data Sheet — Bottle.

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Study record managers: refer to the Data Element Definitions if submitting registration or results information. A stratified randomization of participants based on the time of menstural cycle and breast density. Images will be stripped of identifiers and then coded by a study ID using the third party SanteSoft Dicom Editor software.

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Gadoteric acid is a macrocycle-structured gadolinium-based MRI contrast agent. As a paramagnetic molecule, gadoterate develops a magnetic moment when placed in a magnetic field. This magnetic moment enhances the relaxation rates of water protons in its vicinity, leading to an increase in signal intensity brightness of tissues.

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What is it? Magnetic resonance imaging MRI is a noninvasive medical test that uses very strong magnets and pulses of radio waves to manipulate natural magnetic properties in the body to create images of the part of the body being evaluated. Breast MRI requires intravenous injection of gadolinium-based contrast to evaluate the breast tissue Figure 12looking at both anatomy and blood flow patterns. Normal tissue, cancers, and benign noncancerous findings can enhance on MRI.

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It does not contain all the available information. It does not take the place of talking to your doctor or health care professional. All diagnostic agents have risks and benefits.

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The FDA's review was based on a study showing that at the standard dose 0. The clinical study enrolled 51 pediatric patients in nine centers, with ages spanning from term neonates to 23 months and with normal renal function. It assessed efficacy in a subset of 28 subjects who underwent an MRI examination of brain, spine and associated tissues.

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The originating document has been archived. We cannot confirm the completeness, accuracy and currency of the content. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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It is considered a high-stability agent, and is considered a good choice for patients with lower GFRs see: nephrogenic systemic fibrosis. It is not licensed for this use in North America. Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. Updating… Please wait.

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Learn more at guerbet-us. Stability Down to its Molecular Core. Now approved for pediatric patients less than two years of age including term neonates.

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Important Safety Information 2. Avoid use of GBCAs in these patients unless the diagnostic information is essential and not available with noncontrasted MRI or other modalities. NSF may result in fatal or debilitating fibrosis affecting the skin, muscle and internal organs. Warnings and Precautions.

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